Peptide Science Basics: Evidence-First Education on Peptides and Health

Key Takeaways Ipamorelin and CJC-1295 are both growth hormone secretagogues, meaning they signal the pituitary gland to release more of the body's own growth hormone, but they work through two distinct receptor pathways. CJC-1295 mimics growth hormone-releasing hormone (GHRH) and extends the amplitude and duration of GH pulses; Ipamorelin mimics ghrelin and triggers GH pulse initiation with high receptor selectivity. The single human pharmacokinetic study on CJC-1295, publish

Key Takeaways BPC-157 and TB-500 are both peptides discussed for soft-tissue recovery, but they come from different biological families and act through different mechanisms. BPC-157 is a synthetic 15-amino-acid fragment derived from a protective protein found in gastric juice, and its research base leans toward gut, tendon, and ligament healing. TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring protein, and its research base leans toward cell migration,

Key Takeaways Peptides and anabolic steroids are structurally and mechanistically distinct: peptides are short amino acid chains that signal cells from the outside, while steroids are lipid-based hormones that enter cells and directly alter gene expression. Anabolic steroids are Schedule III controlled substances in the United States; peptides are structurally distinct and are not classified under that same controlled-substance category. Steroids generally produce more direct