Peptide Science Basics: Evidence-First Education on Peptides and Health

Key Takeaways Ipamorelin and CJC-1295 are both growth hormone secretagogues, meaning they signal the pituitary gland to release more of the body's own growth hormone, but they work through two distinct receptor pathways. CJC-1295 mimics growth hormone-releasing hormone (GHRH) and extends the amplitude and duration of GH pulses; Ipamorelin mimics ghrelin and triggers GH pulse initiation with high receptor selectivity. The single human pharmacokinetic study on CJC-1295, publish